Evidence for involvement of TNFR1 and TIMPs in pathogenesis of post-kala-azar dermal leishmaniasis
نویسندگان
چکیده
منابع مشابه
Kala-azar and Post–Kala-azar Dermal Leishmaniasis, Assam, India
remain unknown. S. delphini has rarely been identified in horses, but, as we observed, it may be misidentified by conventional methods. Although colonization or contamination appeared most likely in the instances we describe, these findings suggest that this opportunistic pathogen can be found in horses and might be pathogenic in certain situations. Our findings highlight the importance of usin...
متن کاملNerve involvement in Indian post kala-azar dermal leishmaniasis.
Sir, Post kala-azar dermal leishmaniasis (PKDL) is a wellrecognized sequel of kala-azar in India, developing in approximately 20% cases after a variable time interval of 1 – 5 years (1). The disease occurs chiefly in the eastern parts of India, an area that also has a high prevalence of leprosy. PKDL manifests as symmetrically distributed hypopigmented macules, papules, infiltrated plaques and ...
متن کاملDermoscopy of Post Kala-Azar Dermal Leishmaniasis
© 2018 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow Post Kala‐azar dermal leishmaniasis (PKDL) is a late cutaneous manifestation of untreated or partially treated visceral leishmaniasis (VL) and is caused by the same organism, i.e., Leishmania donovani. It characteristically manifests as macules, nodules, plaques, and facial erythema. A 19‐year‐old male presented with...
متن کاملExtensive Post-Kala-Azar Dermal Leishmaniasis
© 2018 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow A 16‐year‐old male from Bihar had confluent hypopigmented plaques along with erythematous succulent papules on the chin, trunk, and shoulders for the past 8 years. There was relative sparing of axillae, suprapubic, and inguinal regions [Figures 1a‐c]. He had a history of kala‐azar. Skin biopsy and smear showed numero...
متن کاملEvidence for Involvement of Th17 Type Responses in Post Kala Azar Dermal Leishmaniasis (PKDL)
BACKGROUND Post kala-azar dermal leishmaniasis (PKDL), a dermal sequel of visceral leishmaniasis, caused by Leishmania donovani, constitutes an important reservoir for the parasite. Parallel functioning of counter acting immune responses (Th1/Th2) reflects a complex immunological scenario, suggesting the involvement of additional regulatory molecules in the disease pathogenesis. METHODOLOGY/P...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2008
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.2008.03761.x